81335 coverage policies: Medicare and commercial payers

49 active Medicare policies list 81335, and 2 commercial payer policies list it. See each policy's status for the code and its official source. Listing a code is not a coverage decision: read each policy’s source for the requirements that apply.

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Medicare policies listing 81335

LCD · NOVITAS-JH-L35062

Biomarkers Overview

JH · Effective Oct 1, 2015

LCD · NOVITAS-JL-L35062

Biomarkers Overview

JL · Effective Oct 1, 2015

LCD · FIRST_COAST-L39367

Genetic Testing in Oncology: Specific Tests

J9 · Effective Jul 17, 2023

LCD · NOVITAS-JH-L39365

Genetic Testing in Oncology: Specific Tests

JH · Effective Jul 17, 2023

LCD · NOVITAS-JL-L39365

Genetic Testing in Oncology: Specific Tests

JL · Effective Jul 17, 2023

LCD · CGS-J15-L36021

MolDX: Molecular Diagnostic Tests (MDT)

J15 · Effective Oct 1, 2015

LCD · NORIDIAN-JE-L35160

MolDX: Molecular Diagnostic Tests (MDT)

JE · Effective Oct 1, 2015

LCD · NORIDIAN-JF-L35160

MolDX: Molecular Diagnostic Tests (MDT)

JF · Effective Oct 1, 2015

LCD · PALMETTO-JJ-L35025

MolDX: Molecular Diagnostic Tests (MDT)

JJ · Effective Oct 1, 2015

LCD · PALMETTO-JM-L35025

MolDX: Molecular Diagnostic Tests (MDT)

Commercial payer policies listing 81335

2 policies from 2 payers

Summary of the payer’s published policy. Not a coverage determination — confirm with the payer before submitting.

Ambetter

Ambetter policies listing 81335, with the code’s status in each
Policy	Effective	Status of 81335
Concert Genetic Testing: Toxicology and Pharmacogenetics Version BPayerPolicy · AMBETTER-CONCERT-GENETIC-TESTING-TOXICOLOGY-AND-PHARMACOGENETICS-VERSION-B	Not recorded	Referenced

Carelon Medical Benefits Management

Carelon Medical Benefits Management policies listing 81335, with the code’s status in each
Policy	Effective	Status of 81335
Pharmacogenetic TestingClinical Guideline · CARELON-PHARMACOGENETIC-TESTING	Jun 14, 2026	Covered