Biomarkers Overview
JH · Effective Oct 1, 2015
34 active Medicare policies list 81400, and 20 commercial payer policies list it. See each policy's status for the code and its official source. Listing a code is not a coverage decision: read each policy’s source for the requirements that apply.
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JH · Effective Oct 1, 2015
JL · Effective Oct 1, 2015
J9 · Effective Jul 17, 2023
JH · Effective Jul 17, 2023
JL · Effective Jul 17, 2023
JE · Effective Jun 16, 2016
JF · Effective Jun 16, 2016
JJ · Effective Oct 1, 2015
20 policies from 6 payers
Summary of the payer’s published policy. Not a coverage determination — confirm with the payer before submitting.
| Policy | Effective | Status of 81400 |
|---|---|---|
| Concert Genetic Testing: Hematology | Not recorded | Referenced |
| Concert Genetic Testing: Immunology and Rheumatology | Not recorded | Referenced |
| Concert Genetic Testing: Multisystem Genetic Conditions | Not recorded | Referenced |
| Concert Genetic Testing: Nephrology | Not recorded | Referenced |
| Concert Genetic Testing: Neurology |
JM · Effective Oct 1, 2015
J5 · Effective Apr 16, 2016
J8 · Effective Apr 16, 2016
J15 · Effective Oct 1, 2015
JE · Effective Oct 1, 2015
JF · Effective Oct 1, 2015
JJ · Effective Oct 1, 2015
JM · Effective Oct 1, 2015
J5 · Effective Feb 16, 2017
J8 · Effective Feb 16, 2017
J9 · Effective Oct 1, 2015
J6 · Effective Oct 1, 2015
JK · Effective Oct 1, 2015
National · Effective Jan 22, 2026
National · Effective Nov 7, 2024
J5 · Effective Nov 7, 2024
National · Effective Jul 1, 2026
National · Effective Jul 1, 2026
National · Effective Jul 1, 2026
J5 · Effective Jul 1, 2026
JL · Effective Jul 1, 2026
J9 · Effective Jul 1, 2026
J6 · Effective Jul 15, 2026
J9 · Effective Jan 1, 2024
| Not recorded |
| Referenced |
| Concert Genetic Testing: Nutrition and Metabolism | Not recorded | Referenced |
|---|
| Concert Genetic Testing: Ophthalmology | Not recorded | Referenced |
|---|
| Concert Genetic Testing: Orthopedics | Not recorded | Referenced |
|---|
| Concert Genetic Testing: Respiratory | Not recorded | Referenced |
|---|
| Policy | Effective | Status of 81400 |
|---|---|---|
| Infertility | Feb 15, 2024 | Covered |
| Neonatal Hyperbilirubinemia | Aug 10, 2023 | Covered |
| Recurrent Pregnancy Loss | Feb 15, 2024 | Covered |
| Policy | Effective | Status of 81400 |
|---|---|---|
| Expanded Molecular Testing of Cancers to Select Targeted Therapies | Jul 1, 2026 | Covered |
| Genetic Testing for Lactase Insufficiency | May 1, 2026 | Covered |
| Reproductive Carrier Screening for Genetic Diseases | Dec 1, 2025 | Covered |
| Policy | Effective | Status of 81400 |
|---|---|---|
| Carrier Screening in the Reproductive Setting | Sep 19, 2026 | Covered |
| Carrier Screening in the Reproductive Setting | Sep 20, 2025 | Covered |
| Policy | Effective | Status of 81400 |
|---|---|---|
| Cigna Comprehensive Code List | Mar 7, 2026 | Prior auth required |
| Pharmacogenetic Testing | Jul 15, 2026 | Covered |
| Policy | Effective | Status of 81400 |
|---|---|---|
| Tier 2 Molecular Pathology Procedures | Not recorded | Covered |