Biomarkers Overview
JH · Effective Oct 1, 2015
22 active Medicare policies list 81490, and 5 commercial payer policies list it. See each policy's status for the code and its official source. Listing a code is not a coverage decision: read each policy’s source for the requirements that apply.
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JH · Effective Oct 1, 2015
JL · Effective Oct 1, 2015
J9 · Effective Jul 17, 2023
JH · Effective Jul 17, 2023
JL · Effective Jul 17, 2023
J15 · Effective Oct 1, 2015
JE · Effective Oct 1, 2015
JF · Effective Oct 1, 2015
JJ · Effective Oct 1, 2015
5 policies from 4 payers
Summary of the payer’s published policy. Not a coverage determination — confirm with the payer before submitting.
| Policy | Effective | Status of 81490 |
|---|---|---|
| Molecular Biomarker Testing for Noncancer Indications | Aug 26, 2026 | Covered |
| Rheumatoid Arthritis: Biologic Markers and Pharmacologic Assessment | Oct 1, 2025 | Covered |
| Policy | Effective | Status of 81490 |
|---|---|---|
| Concert Genetic Testing: Immunology and Rheumatology | Not recorded | Referenced |
JM · Effective Oct 1, 2015
J5 · Effective Feb 16, 2017
J8 · Effective Feb 16, 2017
J9 · Effective Oct 1, 2015
JH · Effective Dec 12, 2021
JL · Effective Dec 12, 2021
JL · Effective Jan 1, 2024
National · Effective Jul 1, 2026
National · Effective Jul 1, 2026
National · Effective Jul 1, 2026
J5 · Effective Jul 1, 2026
JL · Effective Jul 1, 2026
J9 · Effective Jul 1, 2026
| Policy | Effective | Status of 81490 |
|---|---|---|
| Multi-biomarker Disease Activity Blood Tests for Rheumatoid Arthritis | Jul 1, 2026 | Not covered |
| Policy | Effective | Status of 81490 |
|---|---|---|
| Multi-biomarker Disease Activity Blood Test for Rheumatoid Arthritis | Sep 1, 2025 | Covered |