Biomarkers Overview
JH · Effective Oct 1, 2015
8 active Medicare policies list 81509, and 6 commercial payer policies list it. See each policy's status for the code and its official source. Listing a code is not a coverage decision: read each policy’s source for the requirements that apply.
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JH · Effective Oct 1, 2015
JL · Effective Oct 1, 2015
J9 · Effective Jul 17, 2023
JH · Effective Jul 17, 2023
JL · Effective Jul 17, 2023
J9 · Effective Oct 1, 2015
JL · Effective Jul 1, 2026
J9 · Effective Jul 1, 2026
6 policies from 3 payers
Summary of the payer’s published policy. Not a coverage determination — confirm with the payer before submitting.
| Policy | Effective | Status of 81509 |
|---|---|---|
| Molecular Biomarker Testing for Noncancer Indications | Sep 2, 2026 | Covered |
| Molecular Biomarker Testing for Noncancer Indications | Sep 23, 2026 | Covered |
| Molecular Biomarker Testing for Noncancer Indications | Aug 26, 2026 | Covered |
| Policy | Effective | Status of 81509 |
|---|---|---|
| Maternal Biomarker Screening for Fetal Conditions |
|---|
| May 5, 2023 |
| Covered |
| Noninvasive Down Syndrome Screening | Nov 21, 2023 | Covered |
|---|
| Policy | Effective | Status of 81509 |
|---|---|---|
| Concert Genetic Testing: Prenatal Screening | Not recorded | Referenced |